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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aa05b95f8c9e8031a6021fbd73eb101357c3984e137c4ae5f22e23c2a5110ac' 
  AND token = 'FvgkGjul72bq1TbWdD4u1aOR/jiFzm/0yLnz0NvWfe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}