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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '667e0d17a881aa4f937326edaed47cbd60fd084c6fe39d6d64111fe31b6b2220' 
  AND token = 'wGMPVFv0UIR0kr5LN+V541W8rWKk8fGVCXoH8z9Z2Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}