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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9b22515ee5f3d1f11f8d7a0e9947f4dc5c03742a92cff7076ae32890ddff82' 
  AND token = 'O8eB7YB6jc1K9c14/I2tmPgZYdt74qWvxx0JMiEollg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}