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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '308b55a6dd64c01efc2ea32cf7806e594d1ffcd9ab63f133b884a8e32fcdb3e1' 
  AND token = 'UsfIxvlp/F36aFTJ29emFQO4hr7+kMJ8LiYTwI6yFf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}