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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3aebd8abb6e47b18830ed88587419a0e5e889b058520d2419be6c46530d25583' 
  AND token = 's0WkH0Q7KuKD1BvYfNGYTZSnDDs/B6sdFoj+DI1pKTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}