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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f861b47a41a566b3b7bbb7eb1db001640b61e59f56b7cd5d4b9a3b6af22b5214' 
  AND token = 'U/YmdRox8HISsqsInPon7lmfCz11GpUU7wnVEfn314s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}