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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c80a5224b47605c582808d2596f2bb913a75cae9e8ee9c518bac3216e2cd7473' 
  AND token = 'x2aEPveKAFOocnxYjpL7JAYLSXJucAoYxD+x+5B3m1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}