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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '540f5316cc8efaefb3a03af6fb0cecc9a0d9c3624874c7740ebfbbe280b5eb5e' 
  AND token = 'wCtLOgoYRzGC5S4vjO44S8bc2TxxKeuXK9alEBpwm6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}