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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2bcf875e0efe4290953aff95df55f59727741eba923c35e81a91f64b540f06c' 
  AND token = 'ZEM+m/9fBpBXro1iF5LORfWxMccJXRcNFKN++hHW2sI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}