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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '901392d65c66b1ccf2a0bbbfd24f834c3e596951dd649de6cee26d989d7c9332' 
  AND token = 'TFkYgmuuPH5DeqbYnyRZB3lhVmEbNrCAJDaHSkrp5F4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}