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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c8976d6f3eea94da542152d9928cb0e758bd18f9f48d8f4b85923b92fefa012' 
  AND token = 'NUdKD8sOp2Me8NI9/0LWAWoxmfTsJVCm5j3mODUX1IE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}