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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b3beefc0bd865264fc3b6c092ec73bbade8957c2eedf55940deb293259720b' 
  AND token = 'S1tZwSAvhts9jQ9FqiEwH/I5LiwHOoI0/2BzVsAxwdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}