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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81766f9bcdd56aa5ca24dc6610a25e586289da9c84f6d9538b5de9404c6b5d6b' 
  AND token = 'MBCIr2DPza47maekss39IXbIJrFXaO9HAk+fKWLF1Bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}