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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e10412e7577ee1a943a244e201e22f5a8cf3b5ea3228f0a43caf0cf40e2d286' 
  AND token = 'gGdh8zdlbHJ1UaXPfCHMGql9rXmpTH+GMivoi0e/+Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}