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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b395550dccea8271b5da1dc0154f9c5d880ce4d2fee3029f38c072f0016c6c' 
  AND token = 'QJj6m/KY8a/ylXvaJ8z2ebLt21YJiEvsXEFobycLozc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}