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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f64cd705bac7236e48d2751ba2d89a6920a85b14eaad0389dca4d4da79ff4f5' 
  AND token = 'OEl471hrNFb7gXmYEWJqKDz9hduZKzsDKp199NgnCAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}