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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '925215129ee538d223e917a67980e760dd571e2a3e4fe04f45ee7e77d2eab8c1' 
  AND token = 'jHlkNurSpfdW8dPC1s9qpW9aDj4YQoijzi68KE4mc9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}