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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f891d7c7aef3888895ab9fe7908488082acb8bff49ffc9f8a7d1c04b20c7cd7' 
  AND token = 'ndFs9eVRvIUPkJCa3ag5aG2U6TuetbNBDCJ2YIGf5/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}