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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17b2faa6252f805a5899a3169f045adeed187b1eac2b8725e472e6eedfbb3897' 
  AND token = 'tVm7/DxccRHwlX0QjSj9zAZ260w9ceEynwXOxL3uDRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}