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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '616da65c81d4e04113d27425e2cbd29da3506bc78141442ca70fc1f642606f13' 
  AND token = '1N5RbRuWB0ucTdxlpGjoBXVRGhbFlpy1CIlvpGw+lyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}