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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '865443ed72ca49becb201c4c81844600593632f3448a8379b5ecb9e30d335a8c' 
  AND token = 'B/F/uAL59ANO6066hjlPusfcCUumJlN+czwMIyRn9T8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}