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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e5fa6a20ab0d4b69e5b110b074a4fbfe0e8ee34dc02936ed939d1529b035263' 
  AND token = 'Nq3QOy2p1u+6QILqxu16Y6pWpba9F/QewXsuVK8zdr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}