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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e45a739dfab74e4bc2166aee012c1be57f5e969116f5c2c0ee1a774ce2c2e63c' 
  AND token = '+FvRfpREfVhgLOnx+nYzg7b8qzncpxjgfb352vKwtes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}