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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3545d761962a66ffb2dfae1a6a72fdf8febd9d5133e2f3c1b960bf49b81ba197' 
  AND token = 'frWmBlTs2TCyyBr8YvPTG4WImCK8Rw24i91CvAGKON4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}