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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2d3c9b1ea791ed78bc5b77889cf4ae3477ef090df7c2a4f56fbd73e0cf5c7a' 
  AND token = '/3CPxpJwPpff58VFPDlpbqa5Jj3d+Ojbarj+vu0/OEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}