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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd19379fc31beaed90c26cfc24328d441814aded3831a64c7719b6249d129cd98' 
  AND token = 'mKYKRQhhbaaBBKhnPgYpOFF+dK8ixRRcc2Fz+Mdb/vY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}