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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c5c2bd3d74c4baa667e086c1c9f1a0b04be4a8539411c9750e430f9335760e' 
  AND token = '0jOd6UNrT3XE/OANB0WYH5HusXwUnoS7YtiZQC01QMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}