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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33caa66e15a49bbc5dc68068f71d7f0f0cf30f87f1a3883176c6f4480d4b6c0d' 
  AND token = 'NojZ/vtHFI8xG6mn8/cqxiCzApVZ4IoE2e4reJLXqag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}