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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eac9c156d8937b66078dbb0271bc2130f0e30522f38039a91d3ad21817e3921' 
  AND token = 'Ai6Bd1NoL7oIfa7pQL0xhu76XOAxvHplpaCxExz+UQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}