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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7386e5fb3683c36b143a3b40b5c33b243803d43113e3508c489de5a094d934ee' 
  AND token = 'ShMF4d4bCEnoQeWV+tbKea0QahJcPUmd5PBSX9rPVaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}