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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ec6bd9cc64f77f9f0cc399165571d1724bbc908c45c6836d9ad1db8f91cb379' 
  AND token = 'bCMCz7/OzwOULCyAtYCjjYS2/X0g7+7BcCMmhSiOEfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}