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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '573af6503160f245d54f57633b0a38b6b580b91ebdfdc794ed751a820bafc7a0' 
  AND token = '2UePefMIzW7zyZQExNnMuq/o5rrVY8q7erXiG7dqT3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}