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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f5e5c8f81d15dec89f4249967f3859ae2e1379995c0e8df66233541d784a64' 
  AND token = '+qZDNVdZyOnWg5ZLrj1f/fbSt88iljXoVcgYItPsw/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}