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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ff4f14aadcea480e1811a3c535d3e79a53371e668b1b842bc79789c90f43328' 
  AND token = '0e+FiiVyb0ggJgMyELKD8UzhE3y5/roEb1kk2/4xqZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}