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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666009baf86ec2301606d42838fedfdce6c0abd4d4f83c23a0c8a3ac77c8d459' 
  AND token = '5S+NNPEcyuxizS2ZzRb1L5BBHm5HUrx3e9X4GhuvfJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}