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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1373f5c379b69150a544d611141605cb6de21a9549111a487d59b60569b66c39' 
  AND token = 'BKvoxfCUu5ArnHSDBT2DHCUzgIBupKZ1N9iQNyCqHmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}