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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290cc26e6f99d5b3f2e5dc2d3e7474a3bc164cde87fbaf0d7d3d63d3ad7f2df2' 
  AND token = 'KaC4etDChK7OOB3Fg3A2S0uP3i9QJaoF2SRphWD0b1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}