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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0f318c0df5c702d88b5ef953d04455594022aebb3efddd02dde2a0e62127c00' 
  AND token = 'nlPCffqVjl++3+VN/ibkictleZT4zirZleP2IB1qVww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}