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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cfc22dd42f27526e2eadd7ce981b98c0b37bc1944b8cd6e875460e5581f8565' 
  AND token = 'p4gGkX9/AQAGSfFrwyTdKKgHScYXEQknr8P/V+kF4/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}