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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ffbf57f805ebd459d75e5ce1b1d0f68abd9367de69828e2163e393360f7f4b4' 
  AND token = '4RLamdOWCvg2/C+o92YbLwX6lfIMdeqalSQZpwsDqW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}