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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2154aea5b60669e8331eeb06ece59cf1d5a5ea609168f935cd12f46faccb9301' 
  AND token = '1zUrkLGqPp+I2AIDMBPBxN0LQfyNj1deDUXkvU/+3lQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}