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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69cff582c595c4ef3f08b9d056d18a077e2b3e2afbe6ced3a199be9744e16353' 
  AND token = '45fyf0PBdhS8S2xAo1l4Kc0ewqBqrOfNjFcgDy4Ulvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}