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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1c973d2cf71df2cd4f8278cccd5626898978caff8138a7177d4549c4be28c23' 
  AND token = 'Rb5zs3gqiIQsSsfXbB4kgrigZUtfR0RroTKpGJ/hJUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}