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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e1c42ce60e5553ff5280e465d97df78db446976e8855d71e0eb59f47f9fba1d' 
  AND token = 'SvqE7n5hfHIsMVTFS3nkjjijR8fEN0UAU3fNqmR15xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}