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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b25122eda016561320934f243ed734bfe5e420fe25e9b9dc04a2ce3ee60c24a0' 
  AND token = 'nw8V0Q6JuKD8q7V3ZTPzBmpR+D3sQqeevi2KAjSa1CI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}