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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da00ed68b075403efcce02ed0ad272c93a39f72ea52e805b6470096e60046751' 
  AND token = 'qnL8YxwaQKzz8+j17OnZFBtPNohvSalAeBVvM9jg0ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}