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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff8d49303fa361f676c371b49be251a3e7b8e47edda3da23345e460745da655' 
  AND token = 'B1lI4s2AgBHCkf/cNaKAn+tDv146EI5tfWa3tibbHTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}