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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4edc51c627af5583e7e33883659bd5762bc6a47d4b34b3f4cc2e073d930c807f' 
  AND token = '207V60+GCQEDRns834op6ILuSS8r1HJGz5ASuo1Br2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}