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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3008997a7a0356c2f6193d4bf5b7d52a9e43937c29d8a7d3f8748b7b4ac8a20e' 
  AND token = 'NPifAM4m+SbU+EkFuZSKnQiIkKK3z32qS5Oc/O8az18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}