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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '220cc95819d9b09f03a79a547cb9798eb404baaf0825dbdd764825a0d2b2c6f2' 
  AND token = '+yWgsQ8hzoYa5D7vVAh0tVn89uYzxaSg/vRZR0ZSrp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}